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Clinical consequences include spider telangiectasias and palmar erythema, gynecomastia in men, and abnormal vaginal bleeding and irregular menstrual periods in women

4:389-398 (2013) Hajar-Azhari S, Wan-Mohtar W, Ab Kadir S, Rahim MHA, Saari N

Human very small embryonic-like cells generate skeletal structures, in vivo

Moreover, this option is expensive and difficult to develop in some centers ( Cryopreserving sperm is impossible in prepuberal patients
