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Cellular assays Mammalian cell activity culture and characterization Passages 312 human dermal fibroblast (HDF, Lonza, Basel, Switzerland) were cultured in Dulbecco's Modified Eagle Medium (DMEM, Sigma Aldrich) supplemented with 10% fetal bovine serum (Hyclone, Logan, UT) and 1% penicillin/streptomycin (P/S, Sigma Aldrich) in a 37C, humidified, 5% CO 2 /95% air environment
The discontinuation rate due to adverse events was 6% for CagriSema versus 3.7% for placebo
Quick Overview Retatrutide is a once-weekly peptide
