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An important note: Berberine is a supplement, which isnt regulated or reviewed by the U.S

The studies that achieved improvements in high-intensity (80% O 2 max ) exercise performance used acute doses of 3 to 4 g of l-C or GPL-C ingested between 60 and 90 min before exercise and chronic doses of 2 to 2.72 g/day of l-C for longer periods up to 9 to 24 weeks

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Specifically, the Patient Health Questionnaire (PHQ-9) score for depression dropped significantly from 13.03 to 9.84, and the Fibromyalgia Impact Questionnaire (FIQ) score dropped from 49.55 to 43.03
