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Who should avoid using DSIP

In the human airway smooth muscle cells, co-incubation with BMS-345541 markedly inhibited the NF-B nuclear translocation induced by TNF- and IL-13
Over the last two decades, many studies have examined the underlying mechanisms of curcumins antioxidant properties and its ability to scavenge free radicals, thus reducing cellular oxidative damage (328) showed that curcumin can decrease oxidative stress and inflammation in the liver by augmenting antioxidant enzyme activity (328)

If you do not have any of the conditions below then it is likely that your low vitamin B12 is due to your diet, in which case it is not a medical issue and can be corrected with oral supplements you can buy over the counter or online