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[PMC free article] [PubMed] [Google Scholar] Stammers M, Ivanova IM, Niewczas IS, Segonds-Pichon A, Streeter M, Spiegel DA, Clark J (2020a) Age-related changes in the physical properties, cross-linking, and glycation of collagen from mouse tail tendon

Its one of several typical perimenopausal symptoms, along with hot flushes, mood changes, and sleep disturbances

[2][3] Because of its significant effect on growth and development as well as causing associated medical problems and reduced quality of life, childhood-onset GHD has been treated with replacement therapy for more than 30 years

The lethal concentration (LC 50 ) for HThF cells was ~ 1 M, while the LC 50 for the PTC cell lines was substantially less (0.050.5 M)