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Higher concentrations of ROS accelerated the release of bFGF from the hydrogel in vitro, and the therapeutic effects of the ROS-responsive hydrogel loaded with bFGF were validated using mouse and pig models of ischemiareperfusion injury [337]
In the context of IgG-mediated autoimmune diseases, FcRn maintains high levels of pathogenic auto-Abs in the circulation and tissues via a cellular recycling process that extends the plasma half-life of IgG Abs
The Growth Hormone Receptor: Mechanism of Receptor Activation, Cell Signaling, and Physiological Aspects
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