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This therapy-induced alteration in the microbiota-BA axis not only contributes to severe treatment-related toxicities, such as diarrhea and enterocolitis, but also reshapes the local and systemic immune landscape, potentially influencing therapeutic outcomes (156, 158)

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[DOI] [PMC free article] [PubMed] [Google Scholar] 61.Alam SN, Yammine H, Moaven O, Ahmed R, Moss AK, Biswas B, Muhammad N, Biswas R, Raychowdhury A, Kaliannan K, Ghosh S, Ray M, Hamarneh SR, Barua S, Malo NS, Bhan AK, Malo MS, Hodin RA