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H., Kamboh, A

Studies evaluating transient elastography have demonstrated reproducible performance across a variety of patient populations, including persons with HCV.[14,15,16] Transient elastography is generally considered to be the most accurate noninvasive testing for liver fibrosis in patients with chronic HCV and a patient should be presumed to have cirrhosis if they have a FibroScan stiffness score greater than 12.5 kPa.[4,16] The FibroScan also performs a controlled attenuation parameter (CAP) measurement that estimates the amount of fat in the liver

Dysbiosis impairs the intestinal barrier, increasing its permeability and allowing bacteria and lipopolysaccharides (LPS) from the gut to translocate into the systemic circulation, leading to systemic inflammation (148)