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AD-related pathological A can reach the lungs via the meningeal lymphatic vessels, activate pulmonary B cells via the TLR4/NF-B signaling pathway, and pulmonary memory B cells can infiltrate the frontal cortex of the brain via the CXCL12-CXCR4 axis

For example, an acute inflammatory response drives the transcription factor, NFB, to switch melatonin synthesis from pinealocytes to macrophages/microglia and, upon acute inflammatory resolution, back to pinealocytes

Leaf anatomy on MLE revealed high antioxidant contents such as GSH, AsA, salicylic acid, DPPH radical-scavenging activities, an essential antioxidant in preventing lipid peroxidation

PMID: 38246341