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12,14 This allows for a shift in macrophage activity from M1 (pro-inflammatory) to M2 (reparative)
Enhancing tolerance of broiler chickens to heat stress by supplementation with vitamin E, vitamin C and/or probiotics
T., Giembycz, M

It is found that curcumin can downregulate Bcl-2 and upregulate Bax, promoting the activation of caspases and poly (ADP-ribose) polymerase (PARP), ultimately facilitating caspase-dependent cell death, including osteosarcoma (Dhule et al., 2014), breast cancer (Low et al., 2022), and HeLa cancer cells (Ahmadi et al., 2017)
