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Description
Vitamin B12 deficiency can affect anyone, but some individuals are at higher risk

Redox control at the level of methionine biosynthesis Enzymes catalyzing the two first steps of methionine synthesis, i.e., CGS and CBL, are present only in chloroplasts and are encoded by a single gene while MS are encoded by three genes, with two isoforms being expressed in the cytosol (MS1 and MS2) and one in chloroplasts (MS3) (Figure 1
[1] Jeffrey D Pollard

If you experience fatigue, weakness, memory problems, or have a diet low in B12 (e.g., vegetarian or vegan diets), you might need a supplement
