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Lyse cells by sonication on ice (~10 times for 10 sec each with 1 min rest between bursts to minimize sample heating)

Y., Kajino-Sakamoto, R., Omori, E., Jobin, C

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For instance, Fluplatin@PEG-PE nanoparticles (FP NPs) can degrade mutp53 and trigger endoplasmic reticulum stress, alleviating resistance to cisplatin chemotherapy [99]