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Finally, the diverse immune profiles and tumor heterogeneity across patients may influence the efficacy of anti-PD treatment, highlighting the need for the development of personalized approaches and biomarkers to overcome anti-PD resistance and guide more precise combinational therapeutic decisions to adjuvant PD-1/PD-L1 blockade therapy
doi: 10.1074/jbc.M109.006338 75 CencioniMTChiurchiVCatanzaroGBorsellinoGBernardiGBattistiniLet al
The analysis was performed using FACStarPLUS flow cytometry system and FlowJo software (TreeStar, Ashland, OR, USA)
Implicit solvation was used (PBF model)
