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Lysosomal Destabilizing Drug Siramesine and the Dual Tyrosine Kinase Inhibitor Lapatinib Induce a Synergistic Ferroptosis Through Reduced Heme Oxygenase-1 (HO-1) Levels

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Choice B: Effective penetration into the liver is a necessary pharmacokinetic property for drugs treating hepatic infections

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The combined effects of ionic imbalance and elevated ROS levels cause multiple deleterious impacts culminating in fungal cell death (Phillips et al., 2003

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