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HD affects mainly the large pyramidal neurons of the cerebral cortex and the medium spiny neurons of the striatum
Front Behav Neurosci 16:987697 [DOI] [PMC free article] [PubMed] [Google Scholar] 77.Ma Q (2013) Role of NRF2 in oxidative stress and toxicity
10.1016/j.bmc.2011.12.034 118 KremerovM.DranskM.SnoeckR.BalzariniJ.PomeislK.AndreiG
however, existing medications have limited efficacy and potential side effects, and evidence for non-pharmacological therapies remains limited
