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Journal of Critical Care

Another study using ellagic acid to treat oxygen-glucose deprivation and reoxygenation models of rat cortical neurons cultured in vitro found a significantly reduced volume of cerebral infarction and improved neurological deficit score in rats by increasing the Bcl-2/Bax ratio (Rehman et al., 2019)

Preclinical studies in breast, pancreatic, and triple-negative breast cancer models have demonstrated that combined CDK4/6 and PI3K or mTOR inhibition can overcome monotherapy resistance, suppress proliferation, and induce immunogenic cell death [39,65,66]

Mora, A., Komander, D., van Aalten, D
