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Usually, the portal vein of such laboratory animals does not have culturable bacteria despite the presence of systemic sepsis, suggesting that BT takes place by transfer of intestinal bacteria predominantly into the lymphatic circulation via the intestinal lymph nodes, likely via the specialized M-cells overlying lymphoid aggregates [69, 70]

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There are three classical signal transduction pathways involved in the development of endoplasmic reticulum stress: IRE1, PERK, and ATF6

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B.ChungM

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GI perfusion Gastrointestinal perfusion is vital for delivery of oxygen and nutrients and removal of toxic metabolic byproducts from the gut mucosa

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