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The use of ascorbic acid, vitamin C in excess of the recommended dietary allowance during normal pregnancy should be avoided unless, in the judgment of the physician, potential benefits in a specific, unique case outweigh the significant hazards involved (1)

We also observe that expression of genes encoding mitochondrial proteins are higher in males than females in human cohorts

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Thyroid dysfunction and outcomes in kidney disease There is a growing body of evidence showing that hypothyroidism and other thyroid functional test derangements are associated with higher mortality risk, cardiovascular disease, and worse patient-centered outcomes in the advanced CKD population (Figure 3)