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F., Thursz, M

82 In addition, LNPs can be loaded with both lipophilic and water-soluble therapeutic drugs due to their hydrophilic and phobic properties, where the hydrophilic drugs can be loaded inside, and the lipophilic drugs can be encapsulated in phospholipid bilayers or adsorbed on the surface of liposomes, 83 moreover, such LNPs loaded with therapeutic drugs can increase drug concentrations in tumor cells, reduce therapeutic dose and toxicity, and treatment resistance compared to free drugs

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The acetate structure reduces the rate of degradation of the raw material by peptidases in vivo, improves oral absorption, facilitates its crossing of the blood-brain barrier, reduces oxidative stress and neuroinflammation in the brain, alleviates nerve damage caused by -amyloid protein, and improves cognitive decline problems such as memory loss and slowed thinking