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In contrast, AOD-9604 works directly on adipocytes to enhance lipolysis regardless of appetite or caloric intake

Although there are evidenced-based data supporting certain treatment approaches for patients in clinical studies, the unsolved question in clinical practice remains: "Who is the ideal patient for a given treatment approach?" Thus, treatment of IC/BPS often requires a trial-and-error approach

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These challenges include degradation by cellular nucleases, high renal clearance, and low penetration in biological membranes due to their negative charge