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Description
33.) Lewis, UJ

Neuroprotection Research Investigations in brain injury and neuroinflammation models demonstrated: Enhanced memory formation and consolidation when fused with blood-brain barrier-penetrating peptides Amelioration of memory deficits induced by amyloid-beta or lipopolysaccharide Significant downregulation of hippocampal pro-inflammatory cytokines Potential therapeutic relevance for age-related cognitive decline Critical Research Limitation: Despite extensive animal research spanning metabolic disorders, aging, and physical performance, MOTS-c has NO completed peer-reviewed human clinical trials published in scientific literature

On the access question: We believe patients who have legitimate clinical needs documented injury, inflammatory conditions, immune dysfunction deserve access to evidence-informed therapeutics through licensed, supervised channels

doi: 10.1111/j.1365-2230.2011.04019.x