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Restoration of the tumor suppressor function to mutant p53 by a low-molecular-weight compound

The BPCIA (2010) and the Purple Book The Biologics Price Competition and Innovation Act, enacted as Title VII of the Affordable Care Act in 2010, did for biologics what Hatch-Waxman did for small molecules, though with considerably more complexity

ADH polymorphisms Single nucleotide polymorphisms (SNPs) have been identified at the ADH1B and ADH1C loci with translation of the resulting isoforms having different catalytic efficiencies for ethanol (113, 120) (Figure 6)

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