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Description
GYY4137 inhibits macrophage pyroptosis Synovial macrophage was reported to play a key role in regulating synovial inflammatory responses
However, UPR can also activate downstream apoptotic signaling pathways and promote apoptosis when the damage is persistent and severe or when the extent of the crosstalk network exceeds the resolution capacity of ER loading aberrations (55)

doi: 10.3390/nu11040794

For retinol, this is particularly important
