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In animal research, combined use shows improved results: Quicker formation of granulation tissue and wound closure Decreased edema and inflammation Better tendon-to-bone integration and ligament tensile load Systemic effects on the protection of distant organs, such as the liver and kidney in ischemia-reperfusion

Thus, aging encompasses a constellation of vascular changes, many of which are also observed in diseases of the central nervous system

It plays a vital role in cellular repair, detoxification, and combating oxidative stressfactors that greatly influence skin health and appearance

It is interesting to mention the meta-analysis carried out by Schttker et al., where the association between serum concentrations of 25(OH)D and mortality was investigated in different cohort studies with individuals with differences by age, sex, and country