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This anti-inflammatory effect likely contributes to the neuroprotective effects observed in this study (Al-Beltagi 2021)

[14] Thyronamines have no medical usages yet, though their use has been proposed for controlled induction of hypothermia, which causes the brain to enter a protective cycle and can be useful in preventing damage during ischemic shock

however, 70% of patients develop motor fluctuations after 9 years of CD/LD treatment [5] that are characterized by episodes of suboptimal response to medication, resulting in the reappearance or worsening of their symptoms (OFF episodes) [1]

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