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Recent advances in understanding the pathogenesis of rheumatoid arthritis: new treatment strategies

doi: 10.1016/j.cmet.2017.10.005

The synovium contributes to cartilage repair by recruiting synovial-derived mesenchymal stem cells (SMSCs), which can differentiate into chondrocytes and secrete matrix (McGonagle et al., 2017)

Substitution of three amino acids switches receptor specificity of Gq to that of Gi