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For example, antibodies targeting an epitope (S597-603) downstream of the C terminus of the SARS-CoV RBD markedly enhanced SARS-CoV infection 36,105

Upon activation, HSF1 trimers translocate to the nucleus and bind to heat shock elements (HSEs) in the promoters of target genes, thereby increasing the transcription of HSP70s, which then undergo degradation or re-monomerization (Vihervaara and Sistonen, 2014)

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Sequential clinical study focused on the relationship between GATA1 mutation and history of TMD and AMKL in DS children