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Receptor endocytosis counteracts the development of opioid tolerance

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The diagnostic accuracy of intracranial hemorrhage (PPV: 81.4%), gastrointestinal bleeding (PPV: 92.0%), and ischemic stroke (PPV: 92.2%) has been previously validated in studies utilizing data from the claims data in Korea [4, 21, 22]

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I think you talked about the surgeon specifics a little bit too, Len

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