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however, they can also lead to dilution of ownership

In the cells of extant organisms, the vast majority of the proteins in the mitochondria (numbering approximately 1500 different types in mammals) are coded by nuclear DNA, but the genes for some, if not most, of them are thought to be of bacterial origin, having been transferred to the eukaryotic nucleus during evolution

The systemic administration of KA triggers seizure activity, which leads to a large production of ROS, causing ROS-induced DNA damage, protein oxidation, and lipid peroxidation, and subsequent seizure-induced hippocampal cell death 32,33

Another proposed mechanism involves the regulation of inflammatory cascades