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We argue that viewing MS through the lens of an early onset, slowly progressive cytodegeneration of white and gray matter elements, convolved with a variable overlay of adaptive autoimmunity, could readily explain the entire disease spectrum, and aligns well with emerging new evidence

Gene and protein characterization of the human glutathione S-transferase kappa and evidence for a peroxisomal localization

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NCT03921879, Table 1) Other NAMPT inhibitors, including LSN3154567, STF-31, STF-118804, GNE-617, and CB 300919, have not entered clinical trials due to their high toxicity or low safety