define glutathione s-transferase The role of glutathione-S-transferase in anti-cancer drug resistance Plant glutathione S-transferases: enzymes with
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Sulzer and Zecca, 2000
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The molecular mechanisms of tamoxifen resistance are partially understood and involves ER downregulation, ESR1 mutations, modulation of cell cycle regulators, activation of receptor tyrosine kinases and downstream effectors, and modulation of non-coding RNAs 610

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