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That is roughly triple the placebo response, which sounds impressive until you consider the absolute numbers

GS is constitutively expressed in all cells and has not been studied as extensively as GCL [5]

While mutations of ETC proteins are rarely linked as a direct cause of PD (except for UQCRC1), impaired ETC proteins may not only lead to excessive ROS production, but also cause impeded mitophagy, -Syn aggregation, and apoptosis in PD pathogenesis

Whether you're evaluating a supplement, modifying your training, or testing any health intervention, understanding this framework will transform how you approach self-experimentation